Dynamic modeling of the acrylic acid synthesis from renewable resources
Integration of life sciences & engineering
Integration of Life Sciences & Engineering - Poster (T5-P)
Keywords: Sugar cane, biotechnological processes, experimental design, acrylic acid
A great challenge related to preservation of the environment is the exhaustion of raw material based on oil. The population growth and the associate demand for fuels and chemicals have increased the research and development for the use more diversified of renewable raw material. With the synthesis of chemical products through biotechnological processes is possible to discovery and to explore innumerable routes that can be used to obtain products of high added value. These routes form parallel and alternative ways for the production of the desired product, what makes easier the environment preservation and a rational use of renewable feedstock.
The acrylic acid, know as propenoic acid, is one of the most important industrial chemical product. Usually it is obtained by oxidation of propylene. A possible alternative way is the fermentation from sugar cane. Bearing this in mind, the purpose of this work is the model development for the biotechnological process of acrylic acid synthesis. The full detailed model is a set of differential partial equations composed by the reactor equations together with the description of the microorganism metabolism aiming to follow the evolution of intracellular variable that are difficult to measure. The whole set of equations is solved coupling the Orthogonal Collocation Method to discretize the radial ordinates with the Method of Lines to integrated the system of equations by a stiff integrator.
In biotechnological processes, a great number of factors can influence the income productivity and conversion. Normally, it is not evident which of these factors are most important. In this work it is used the multivariate analysis techniques, as experimental design together with a detailed deterministic model. With such procedure is possible, beyond the determination of the important factors of the process, to identify the structures of control for differentiated strategies of operation. The mapping of the dynamics of the developed process is made using techniques of factorial design together with the methodology of Plackett-Burman. It is shown that it is possible to increase the process performance by choosing optimized conditions for the reactor operation.
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Presented Wednesday 19, 13:30 to 15:00, in session Integration of Life Sciences & Engineering - Poster (T5-P).