Topical A: Systems Biology

Session 284 - In Silico Systems Biology III
A critical component of systems biology is the development of in silico approaches to understand systems of interest. For this session, papers discussing novel uses of in silico methods to understand biological systems, as well as the development of new technologies and algorithms for in silico systems analysis are welcome. Research including experimental work is particularly encouraged.
Chair:Ranjan Srivastava
CoChair:Jeffrey D. Varner
 Modeling the ErbB Signaling Network in MCF-7 Breast Cancer Cells and Analysis of Ligand-Dependent Responses
Marc R. Birtwistle, Mariko Hatakeyama, Noriko Yumoto, Jan B. Hoek, Boris N. Kholodenko, Babatunde A. Ogunnaike
 Simulation of Non-Specific Protein-Mrna Interactions in the Eif4f Translation Initiation Factor Complex
James Magee, Jim Warwicker
 A General Model for Ultrasensitivity Arising from Single Protein Multisite Modifications
Xiaoxia (Nina) Lin, Yuan Gao, Yaoyun Shi, George M. Church
 Spatial Organization of Egf Receptors and Its Implications for Signaling
Kapil Mayawala, Dionisios G. Vlachos, Jeremy S. Edwards
 Break
 How T Cells Hunt for Antigen in Lymphoid Tissue
Bo Jin, Alan S. Perelson, Arup K. Chakraborty
 From Ligand Binding to Transcription Activation: Insilico Simulation of Tumor Necrosis Factor-Induced Nuclear Factor Kappa B Activation Using Ibrena Software Package
Gang Liu, Sriram Neelamegham
 Antigen Quality Regulates Signaling and Degradation in the Immunological Synapse
Jayajit Das, Saso Cemerski, Jason W. Locasale, Phoebe Arnold, Daved Fremont, Paul Allen, Andrey S. Shaw, Arup K. Chakraborty

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