Topical A: Systems Biology | |||
| Session 152 - Synthetic Systems Biology II | |||
| Systems biology is the study of whole biological ensembles, rather than isolated parts, in order to build a predictive biological understanding of a defined system’s behavior. Synthetic biology has been defined as the design and construction of systems that exhibit complex dynamical or logical behavior. The intersection between these two fields is likely to significantly enhance efforts in design-based biological engineering and therefore greatly increase human capability. This session will cover current applications of systems biology theory and techniques to aid in the design of synthetic biological systems. In addition, efforts that apply synthetic biology research as new tools to expand systems-level understanding or as new concepts in systems biology are of interest. | |||
| Chair: | Jason Haugh | ||
| CoChair: | Christina Smolke | ||
| 152a | Optimizing Biological Circuits: Integrating Rational Design with Directed Evolution Eric L. Haseltine, Frances H. Arnold | ||
| 152b | HIV's Evolution of Resistance to Antiviral Gene Therapy Is Predictable and Utilizes Novel Cooperative Mechanisms Joshua N. Leonard, David V. Schaffer | ||
| 152c | Engineering Ligand-Regulated Rnai Substrates as Novel Tools for Probing and Programming Cellular Systems Chase L. Beisel, Christina Smolke | ||
| 152d | Tunable Promoters for the Synthesis and Analysis of Functional Gene Networks Curt R. Fischer, Hal S. Alper, Elke Nevoigt, Gregory N. Stephanopoulos | ||
| 152e | Computational Design of Synthetic Biological Circuits Madhukar S. Dasika, Costas D. Maranas | ||
| 152f | Computer Aided Design of Modular Protein Devices: Logical "and" Gene Activation Howard Salis, Yiannis N. Kaznessis | ||
| 152g | In Vitro Integration of Multiple Metabolic Systems for the Production of Membrane Proteins Jessica J. Wuu, James R. Swartz | ||
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