Topical 2: Discover, Development and Delivery of Medicines

Session 641 - Process Development Tools for Pharmaceutical Process Development
The pharmaceutical engineering lab is endowed with on-line probes that hold the promise of rapid process development without sacrificing process understanding. This session will focus on the application of these lab tools in solving process problems.
Chair:Shailendra V. Bordawekar
CoChair:Brent Nielsen
CoSponsor(s):Manufacturing
 Shear-Induced Compaction of Pharmaceutical Formulations
Marcos Llusa, Bodhisattwa Chaudhuri, M. Silvina Tomassone, Mobeen Faqih, Amit Mehrotra, Fernando J. Muzzio
 A Numerical Investigation of Air Flow during Tablet Compression
Douglas M. Kremer
 Combined Experimental and Modeling Study of a Kinetic Resolution
John W. Shabaker, Srinivas Tummala, Erqing Tang, Olav Lyngberg, Lindsay Hobson
 On-Line Ftir Measurements for the Pilot-Plant Scale-up of a Borane Reduction Process
Camille O. Anderson, George Zhou, Brian Phenix
 Development of a Generic Process Model for Dynamic Simulation of Protein Downstream Processes
Constantin Frerick, Peter Kreis, Andrzej Górak
 Catalyst Trap Microreactor for Pharmaceutical Hydrogenation
Shaun M. McGovern, G. Harish, Ronald S. Besser
 Ion Exchange Process Development with Pat
James Marek, Shekhar K. Viswanath, John Tolle

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