Pharmaceuticals |
|||
| Session 651 - Modeling in the Pharmaceutical Industry II | |||
| The development of pharmaceuticals involves the development of both process and chemistry/formulation to produce the active pharmaceutical ingredient/final drug product. We invite contributions from industry and academia that address system-level process simulation (cycle time analysis, mass and energy balances, equipment usage, scheduling etc.) and/or more detailed unit operations modeling during process development and scale-up in pharmaceutical synthesis and formulation (e.g. reaction steps, kinetics, solvent chasing, crystallization, filtration, drying). Particular consideration will be given to examples of model development from laboratory data with model validation during scale-up and clear savings or greater process understanding as a result of process modeling. | |||
| Chair: | Richard Schild | ||
| CoChair: | Christopher L. Burcham | ||
| 651a | Application of Quality by Design Principles In the Model Predictions for Scale-up of Tablet Film Coating Andrew Prpich, Mary T. Am Ende, Thomas Katzschner, Veronica Lubczyk, Holger Weyhers, Georg Bernhard |
||
| 651b | Use of Molecular Modeling In the Formulation of Suspensions Jamie T. Konkel, Allan S. Myerson |
||
| 651c | Use of Pharmacokinetic/pharmacodynamic (PK/PD) Modeling to Aid Formulation Selection Larissa A. Wenning, Eseng Lai, Tami Crumley, Tian-Quan Cai, Fang Liu, M. G. Waters, Shaun Fitzpatrick, Julie Stone |
||
| 651d | Computer Aided Modelling in Pharmacokinetics as a Topical Issue Michael Wulkow, Regina Telgmann |
||
| Break |
|||
| 651e | Modeling of Tablet Dissolution Attendant to Tablet Microstructure Using a Multi-Process F-D Method Dan Braido, Alberto Cuitino |
||
| 651f | Finite Element Analysis of Tablet Compaction Using a Modified Material Plasticity Model Tuhin Sinha, Jennifer S. Curtis, Bruno C. Hancock, Carl R. Wassgren |
||
| 651g | Modeling of the Compaction of Confined Powder Beds Using a Modified Quasi-Continuum Approach Athanas A. Koynov, Alberto Cuitino |
||
See more of Food, Pharmaceutical & Bioengineering Division
See more of The 2008 Annual Meeting