Amundson's legacy, that came about from the early fifties of the last century, changed Chemical Engineering into a fundamental engineering discipline strongly grounded in the application of mathematics. Quantitative frameworks flourished featuring linear and nonlinear analysis as well as computational methods. The broad-based thinking led to an expansion of the scope of chemical engineering far beyond those envisaged by the founding fathers of the profession.

A new paradigm has clearly overtaken Chemical Engineering in the last two decades ushering in numerous new and exciting problems for chemical engineers in the biological, nano- and molecular sciences. In this talk it is my objective to show the strong influence of Amundson's legacy in numerous areas of current activity in the biological field.