A general mixed-integer nonlinear programming model (MINLP) is developed in this study for synthesizing water networks in batch processes. The proposed model formulation is believed to be more comprehensive than the available ones. Not only the interactions between the discontinuous water-reuse and wastewater treatment systems are described in detail, but also a batch scheduling component is incorporated. The resulting optimal design specifications include: the short-term production schedule, the number and sizes of buffer tanks, the physical configuration of pipeline network, and the operating policies of water flows. The network structure can also be strategically manipulated by imposing suitable logic constraints. An illustrative example will be presented to demonstrate the effectiveness of this approach.