Topical A: Systems Biology

Session 49 - Synthetic Systems Biology I
Systems biology is the study of whole biological ensembles, rather than isolated parts, in order to build a predictive biological understanding of a defined system’s behavior. Synthetic biology has been defined as the design and construction of systems that exhibit complex dynamical or logical behavior. The intersection between these two fields is likely to significantly enhance efforts in design-based biological engineering and therefore greatly increase human capability. This session will cover current applications of systems biology theory and techniques to aid in the design of synthetic biological systems. In addition, efforts that apply synthetic biology research as new tools to expand systems-level understanding or as new concepts in systems biology are of interest.
Chair:Christina Smolke
CoChair:Jason Haugh
 Genetic Circuits to Build Biopolymers
Christopher Voigt
 Substrate Specificity and Domain Interaction of the 6-Deoxyerythronolide B Synthase
Alice Yu-Chieh Chen, Chaitan Khosla
 Re-Engineering in Vivo Signal Processing
Stephen A. Chapman, Anand R. Asthagiri
 Biosynthesis of Cadmium Sulfide Semiconductor Nanocrystals
Seung Hyun Kang, Ashok Mulchandani, Wilfred Chen
 A Detailed Kinetic Model for a Bistable Genetic Network
Aditya Pratap Singh, Jeremy S. Edwards
 Enhancement of Cellular Memory by Reducing Stochastic Transitions
Murat Acar, Attila Becskei, Alexander van Oudenaarden
 Stochastic Simulation Analysis of Metabolic Channeling for the Production of R-1,2 Propanediol
Robert J. Conrado, Thomas J. Mansell, Jeffrey D. Varner, Matthew P. DeLisa

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