Engineering Fundamentals in Life Science | |||
| Session 235 - Gene Therapy and Delivery (I) | |||
| This session will be devoted to the development of improved methods of gene transfer using both viral and non-viral approaches. Topics of interest include, but not limited to design of novel formulations for improved gene delivery, determination of rate-limiting steps of gene transfer, targeting of gene transfer vectors, methods for production and purification of viral and non-viral vectors and gene transfer to stem cells for tissue engineering applications. This session has been very well attended in previous years. | |||
| Chair: | Stelios T. Andreadis | ||
| CoChair: | Joseph M. Le Doux | ||
| 235a | Relationships between Molecular Properties of Polymer-Oligonucleotide Complexes and Cellular Antisense Activity Sumati Sundaram, Li Kim Lee, Mark E Hwang, Charles M. Roth | ||
| 235b | Engineering Adeno-Associated Viral Vectors with Novel Cell Tropisms James T. Koerber, David V. Schaffer | ||
| 235c | Engineering Cell Lines for the Production of Highly Replication Defective Herpes Simplex Virus Type 1 Vectors Kyle G. Grant, David M. Krisky, Mohammad Ataai, Joeseph Glorioso III | ||
| 235d | Flow-Enhanced Measurement of Virus Infectivity Ying Zhu, John Yin | ||
| Break | |||
| 235e | Linear-Dendritic Hybrid Polymers for Targeted Gene Delivery to Antigen-Presenting Cells in Vivo Kris C. Wood, Robert Langer, Paula T. Hammond | ||
| 235f | Controllable Concentration Gradients by Spatially Patterned Gene Delivery Tiffany Houchin-Ray, Lonnie D. Shea | ||
| 235g | Rapid Modification of Retrovirus Surfaces for Targeted Gene Delivery Nimisha Gupta, Joseph M. Le Doux | ||
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