Topical 3: 2006 Annual Meeting of the American Electrophoreses Society (AES)

Session 218 - Advances in Proteomics: New Technologies I
Systematic studies of gene expression patterns play a vital role in understanding the complex interactions associated with the global response of cells, tissues, and organisms to stimuli or mutations. While recent developments have allowed these patterns to be investigated at an unprecedented level of detail, further advances are needed in order to fully illuminate the interplay among the many factors governing cellular response. Specifically, new technologies are needed with the capability of providing quantitative information with greatly enhanced levels of sensitivity and throughput. This session will focus on the development of these proteomic technologies and their application to biotechnology. Of particular interest are papers describing advances in gel-free protein separations, novel protein stains, methods of analyzing membrane proteins, mass spectroscopic methods for resolving mixtures of peptides, high-throughput antibody creation and optimization, the development of protein-detecting microarrays, and other related technologies. Papers are also sought that present research on the application of proteomics to the study of bacterial, animal, and plant cell cultures, and especially proteomic analysis of post-translational modifications.
Chair:Wayne F. Patton
 Characterisation of Hep-G2 Conditioned Medium for Enhanced Mesoderm Differentiation of Es Cells: Application to Skeletal Tissue Engineering
Yunyi Kang, Yu-shik Hwang, Athanasios Mantalaris
 De Novo Peptide Identification Via Mixed-Integer Linear Optimization and Tandem Mass Spectrometry
Christodoulos A. Floudas, Peter A. DiMaggio
 Dynamic Quantitative Analysis of the Nucleolar Proteome Using an Isobaric Mass Tagging Approach
Bing Xie, Eric R. Kershnar, Craig Parman, Rixin Wang, Ed Papacoda, Jennifer Maloney, Cesar E. Guerra, Paul M. Kaplan, Brian T. Chait, Paul M. Lizardi, Martin J. Mattessich
 Enhancing Shotgun Proteomics Data Analysis with Bioinformatics Tools: Application to Cyanobacterial Proteomics
Martin E. Barrios-Llerena, Saw Yen Ow, Poh Kuan Chong, Chee Sian Gan, Ambrosius P. Snijders, Kenneth F. Reardon, Phillip C. Wright
 Novel Selective Fluorescent Gel Stains for Improved Detection of Phosphoproteins
Susan E. Kramer, Eva Golenko, Alvydas Mikulskis, Wayne F. Patton
 Optimization of Chip-Based Infusion Nanoelectrospray Tandem Mass Spectrometry for the Rapid Analysis of Complex Proteomes
Ana G. Pereira-Medrano, Alistair Sterling, Ambrosius P. Snijders, Kenneth F. Reardon, Phillip C. Wright

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