Bioengineering

Session 169 - Advances in Protein Engineering (I)
The focus of this session is to reflect the latest advances in protein engineering and design. Suggested topics include, but are not limited to: (1) Development of high throughput screen/selection for protein engineering; (2)Development of novel protein engineering methods; (3) Protein engineering via directed evolution; (4) Structure- or sequence-based and computational protein engineering and design; (5) Applications of protein engineering.
Chair:Lianhong Sun
CoChair:Scott Banta
CoSponsor(s):Catalysis and Reaction Engineering Division
 Understanding the Reaction Mechanism of Protein Splicing in Order to Gain Insights for the Engineering of Inteins
Brian Pereira, Philip Shemella, Patrick Van Roey, Marlene Belfort, Victoria Derbyshire, Saroj Nayak, Georges Belfort, Shekhar Garde
 Antibody Affinity Maturation Using Computational Protein Design
Shaun M. Lippow, Bruce Tidor, K. Dane Wittrup
 Computation-Guided Design of Arac Regulatory Protein Effector Specificity
Hossein Fazelinia, Patrick C. Cirino, Costas D. Maranas
 Application of the Consensus Concept for Increased Thermostability of Enzymes
Eduardo Vazquez-Figueroa, Javier Chaparro-Riggers, Karen M. Polizzi, Andreas S. Bommarius
 Break
 A General Method to Directly Improve Kinetic Stability of Enzymes without Reducing Activity
Philippa J. Reeder, Christopher Bystroff, Jonathan S. Dordick
 Engineering Transcription Factors with Novel DNA-Binding Specificity Using Comparative Genomics
Tasha Desai, Christopher V. Rao
 Genetic Selection of Stable Single-Chain Immunotherapeutics in the Cytoplasm of Escherichia Coli
Adam C. Fisher, Matthew P. DeLisa

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