Engineering Fundamentals in Life Science

Session 586 - Drug Delivery (II)
This session highlights recent research efforts in the broad area of design, characterization (in vitro and in vivo), and development of drug delivery systems with multi-functional properties for targeted and sustained drug delivery. Topics of interest include, but are not limited to: Effects of chemical structure and/or physical properties of drug delivery systems on loading efficiency and release kinetics; functionalizing drug carriers with moieties for specific targeting; blood circulation time and biodistribution of drug-carrier complexes after systemic injection; in vitro and in vivo studies of cellular uptake.
Chair:Efrosini Kokkoli
CoChair:Stavroula Sofou
 The Interplay of Drug, Polymer, and Solvent Properties on the Release Characterisitics of Membrane-Based Systems
Anthony J. McHugh, Decheng Ma, Michael Marsh
 Targeting the Breast Cancer Microenvironment Using Interleukin-12 Conjugated Pamam Dendrimers
Kelsey Yee, Erin Rieke, Stuart Helfand, Christine J. Kelly
 Nanoparticles for Targeted Delivery to Prostate Cancer Cells
Aleksandar F. Radovic-Moreno, Benjamin A. Teply, Jason Fuller, Frank Gu, Etgar Levy-Nissenbaum, Robert Langer, Omid C. Farokhzad
 Recognition of the Size of Polymer Drug Carriers by Macrophages
Julie Champion, Samir Mitragotri
 Break
 Oral Delivery of Insulin Bioconjugates Using Intelligent Complexation Hydrogels
Justin P. Shofner, Nikhil J. Kavimandan, Nicholas A. Peppas
 Validation of a Model Predicting the Influence of Cyclodextrins on Oral Bioavailability: Comparison with in Vitro and in Vivo Data
Ece D. Gamsiz, Avinash G. Thombre, Lee A. Miller, Rebecca L. Carrier
 A Release Rate Study for Controlled Drug Delivery Using Niosomes
Kristina O. Dearborn, Ryan G. Toomey, Michael D. VanAuker, Norma Alcantar

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