Topical 2: Discover, Development and Delivery of Medicines | |||
| Session 410 - Separations in Biopharmaceutical Downstream Processing I | |||
| The focus of this session will be the downstream separation processes such as MF/UF, chromatography (ion exchange, reverse phase, size exclusion, affinity), crystallization, etc. | |||
| Chair: | Kathleen Mihlbachler | ||
| CoChair: | Todd Menkhaus | ||
| CoSponsor(s): | Pharmaceuticals (See also Topical 2) | ||
| 410a | Comparison of a New Continuous Chromatographic Solvent Gradient Process for Bioseparations with Conventional Processes Guido Stroehlein, Lars Aumann, Abhijit Tarafder, Thomas Mueller-Spaeth, Massimo Morbidelli | ||
| 410b | Scale down Model Demonstrates High Prodcut Throughputs with Disposable Anion Exchange Chromatography Jeff D. Mora, Uwe Gottschalk, Oscar Reif, Joe Zhou, Felix Solamo, Shinta Dermawan, Tony Hong, Tim Tressel | ||
| 410c | Downstream Separation and Scale-up Challenges for E.Coli-Derived Biopharmaceuticals – an Industrial Study on Development of an Antibody Fragment (Fab) Process Abdul Wajid, Daljit Narindray | ||
| 410d | A Toolbox for Efficient Release and Recovery of Therapeutic Proteins from the Periplasm of Pseudomonas Fluorescens Anant Patkar, Subrata Sen, Mike Chappell, Yuk Chun Chiu, Jeff Allen, Jefry Shields | ||
| 410e | Diverse Transgenic Plant Hosts Challenge Downstream Process Development Zivko L. Nikolov, Susan L. Woodard, Lisa R. Wilken, Steve G. White, Georgia Barros | ||
| 410f | High Throughput Protein Purification Using Negative Mode Hydrophobic Interaction Chromatography Jennifer McNay, Kenneth Audo, Kevin Bailey | ||
| 410g | Separation of Pharmaceutical Process-Related Impurities by an Organic Solvent Nanofiltration Membrane Cascade Justin Chun-Te Lin, Ludmila G. Peeva, Andrew G. Livingston | ||
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