Topical 2: Discover, Development and Delivery of Medicines

Session 683 - Advances in Cell Culture and Bioreactors
Recent advances in the development and design of mammalian cell reactors will be presented.
Chair:Sanjeev Katti
CoChair:Dhinakar Kompala
CoSponsor(s):Pharmaceuticals (See also Topical 2)
 Optimization of in Vitro Erythropoieis for Genotoxicity Testing
Joe Shuga, Jing Zhang, Leona Samson, Harvey Lodish, Linda Griffith
 Model-Based Optimisation of Mammalian Cell Cultures: a Case Study for Optimising Glucose and Glutamine Fed-Batch Profiles for CHO-IFNγ Cell Line
Carolyn M. C. Lam, Danny C. F. Wong, Miranda G. S. Yap, Efstratios N. Pistikopoulos, Athanasios Mantalaris
 Liver Endothelial Cells Promote Ldl-R Expression and the Uptake of Hcv-like Particles in Primary Hepatocytes
Yaakov Nahmias, Monica Casali, Laurent Barbe, Francois Berthiaume, Martin L. Yarmush
 Insights into Hepatic Metabolism from Flux Balance and Pathway Analyses
Hong Yang, Charles M. Roth, Marianthi Ierapetritou
 Engineering Cancer-Specific Cis-Acting Intronic Regulators of Alternative Splicing as Novel Tools for Disease Detection and Treatment
Stephanie Culler, Christina Smolke
 Effects of Igf-1 Modified Ehd Networks on Myoblastic Cell Proliferation
Erin E. Falco, Eve M. Rubinstein, J. Scott Roth, John P. Fisher
 A Chemically Inducible Cucumber Mosaic Virus Amplicon Expression System for Production of Recombinant Human Therapeutics in Transgenic Plant Cell Cultures
Ting-Kuo Huang, Michael A. Plesha, Mysore R. Sudarshana, Sandra L. Uratsu, David M. Tricoli, Bryce W. Falk, Abhaya M. Dandekar, Alan P. Jackman, Karen A. McDonald

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